Mar 28, 2007 (CIDRAP News) – Hong Kong officials concluded that a baby girl who was recently infected with H9N2 avian influenza—a strain believed to have pandemic potential—probably contracted it from birds, according to recent reports.A 9-month-old girl who was hospitalized with respiratory symptoms twice in recent weeks tested positive for an H9N2 infection Mar 20. The girl had only a mild illness but was treated in isolation at Princess Margaret Hospital, the Hong Kong Department of Health reported in a Mar 22 statement. At the time of her second hospitalization she had respiratory syncytial virus, the statement said.Dr. Thomas Tsang, controller of the Hong Kong Centre for Health Protection, said tests had ruled out the possibility of human-to-human transmission in the girl’s case, according to a Mar 24 news release from Hong Kong’s Information Services Department.Tsang said genetic analysis of the H9N2 virus showed that it was entirely of avian origin, suggesting that the child contracted it directly from a bird, the release said. Because the girl had no contact with wild birds before her illness, she may have caught the virus at a bird market that she visited several times with her family, Tsang said.He also said tests on respiratory specimens from a healthcare worker and three children who were in the same hospital cubicle with the baby in early March tested negative for H9 viruses, and her family had no symptoms.Meanwhile, leading virologist Robert Webster warned this week that H9N2 is an “insidious” virus that needs close monitoring because it could trigger an outbreak in humans, according to a Mar 27 Bloomberg News report.H9N2 is far less known than the deadly Asian strain of H5N1 virus, which has killed at least 169 people and millions of poultry in Asia and Africa in the past few years. But Webster told Bloomberg, “H9N2 is an insidious virus. This is the one that’s far more dangerous in some ways. It doesn’t get much attention because it doesn’t kill chickens and doesn’t kill humans.”He said H9N2 can spread among pigs and infects chickens without making them sick. On the “hit list” of viruses, he added, “H5N1 is at [the] top, and H9N2 is right behind. Then come H7N7 and H2N2.”At least three cases of H9N2 illness, all of them mild, have occurred in Hong Kong children in recent years. Two girls were infected in 1999 and a 5-year-old boy had the virus in 2003.Robert L. Atmar, MD, a Baylor College of Medicine professor who has participated in clinical trials of an H9N2 vaccine, said human H9N2 illnesses may be less rare than the record suggests. Seroprevalence studies in China in the 1990s found H9 antibodies in 2% to 3% of the population, which suggests that some cases are missed, he told CIDRAP News via e-mail.Atmar, a professor in the Departments of Medicine and of Molecular Virology and Microbiology, also commented that the finding of a case in a 9-month-old child was “a little surprising unless she was toddling around the market. Usually, cases of avian influenza have followed close contact with infected poultry. H9N2 viruses are common in bird markets.”See also:Mar 20 CIDRAP News story “Baby in Hong Kong infected with H9N2 avian flu”Journal of Clinical Microbiology report on Hong Kong H9N2 case in 2003
With his two chief competitors optioned to Triple-A in Friday night, Johnny Giavotella is the presumptive winner of the Angels’ second baseman job and Taylor Featherston, who has never played above Double-A, is his backup.Both are feel-good stories for landing their respective positions considering Giavotella hasn’t had a season with more than 200 at-bats in the majors.Giavotella, 27, beat out Josh Rutledge, who entered spring training as the favorite to replace Howie Kendrick but was optioned to Triple-A along with Grant Green, who was also in the running to start at second base. Other Angels optioned to Triple-A on Friday night were highly regarded starting pitcher Andrew Heaney and infielder Kyle Kubitzka.Angels manager Mike Scioscia had high praise for Featherston, but the Angels had more incentive to keep him on the major league roster because if they hadn’t, he could have been claimed off waivers. The 25-year-old was a Rule 5 draft pick from the Colorado Rockies organization this winter, meaning the Rockies could have reclaimed him if he cleared waivers after the Angels sent him to the minors. Featherston, who was selected in the fifth round of the 2011 draft, will likely play a significant bench role for the parent club considering his versatility in the infield. “I think Taylor has shown, first of all, extraordinary athleticism at three positions. That is special on the defensive side,” Scioscia said. “His defense plays at any level, whether he’s at rookie ball or on a World Series team. He can play. The offensive side,I think, is still developing, but he’s an exciting talent and we’ll see where it leads.”Neither Featherston nor Giavotella were in the Angels’ organization last season. Giavotella, a second-round pick in 2008, was acquired in December from the Royals for reliever Brian Broderick, who was signed out of the Mexican League shortly beforehand.Giavotella hit .308 in spring training, but during his 465 plate appearances for the Royals over parts of four seasons, he owns a slash line of .238/.277/.334, which doesn’t exactly inspire confidence. Mattingly on analytics Dodgers manager Don Mattingly acknowledged some of the differences in how his bullpen is viewed by the relievers themselves versus management.The goal for relievers is, obviously, to be a closer. But analytics by which relievers are judged by front office executives looking for peak performance in the most important situations reveal that some of the more pivotal pitches in a given game aren’t necessarily in the ninth inning. The ultimate dictator for players, however, is the pay scale, which favors closers above all others in the bullpen. “(Analytics) look at high-leverage situations and that may be the seventh, it may be the eighth, but as far as (pitchers) are concerned, they look at it differently,” Mattingly said. “Them knowing their role and knowing they’re that guy. … Right now you get rewarded for saves.” Pitcher releasedPitcher Barry Enright, who has spent time in the Dodgers’ and Angels’ organizations over the last two years, has been released by the Dodgers.The right-hander, with a career 5.57 ERA in the majors, joined the Angels’ organization in 2012, but signed with the Dodgers in July of last year before finishing last season with the Phillies’ organization. Newsroom GuidelinesNews TipsContact UsReport an Error
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